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Protein Localization by Actin Treadmilling and Molecular Motors Regulates Stereocilia Shape and Treadmilling Rate

We present a physical model that describes the active localization of actin-regulating proteins inside stereocilia during steady-state conditions. The mechanism of localization is through the interplay of free diffusion and directed motion, which is driven by coupling to the treadmilling actin filam...

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Bibliografiske detaljer
Main Authors: Naoz, Moshe, Manor, Uri, Sakaguchi, Hirofumi, Kachar, Bechara, Gov, Nir S.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599822/
https://ncbi.nlm.nih.gov/pubmed/18936243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.143453
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