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Structural Studies of Interactions between Cardiac Troponin I and Actin in Regulated Thin Filament using Förster Resonance Energy Transfer

The Ca(2+)-induced interaction between cardiac troponin I (cTnI) and actin plays a key role in the regulation of cardiac muscle contraction and relaxation. In this report we investigated changes of this interaction in response to strong crossbridge formation between myosin S1 and actin and PKA phosp...

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Detalhes bibliográficos
Main Authors: Xing, Jun, Chinnaraj, Mathivanan, Zhang, Zhihong, Cheung, Herbert C., Dong, Wen-Ji
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599808/
https://ncbi.nlm.nih.gov/pubmed/19053249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801492x
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