The antichlamydial, antiviral, and antiproliferative activities of human gamma interferon are dependent on the integrity of the C terminus of the interferon molecule.

The effects of recombinant human gamma interferon (rHuIFN-gamma; two identical monomers of 140 residues in length) and of two re-engineered C-terminal variants, rHuIFN-gamma Tetra-Ser (residues 129 to 132 replaced by serine) and rHuIFN-gamma 125 (two identical monomers of 125 residues each with the...

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Εκδόθηκε σε:	Infect Immun
Κύριοι συγγραφείς:	de la Maza, L M, Peterson, E M, Burton, L E, Gray, P W, Rinderknecht, E, Czarniecki, C W
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1987
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3117689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.11.2727-2733.1987
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