Role of Cellular FKBP52 Protein in Intracellular Trafficking of Recombinant Adeno-associated Virus 2 Vectors

We have reported that tyrosine-phosphorylated forms of a cellular protein, FKBP52, inhibit the second-strand DNA synthesis of adeno-associated virus 2 (AAV), leading to inefficient transgene expression from recombinant AAV vectors. To further explore the role of FKBP52 in AAV-mediated transduction,...

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Main Authors: Zhao, Weihong, Zhong, Li, Wu, Jianqing, Chen, Linyuan, Qing, Keyun, Weigel-Kelley, Kirsten A., Larsen, Steven H., Shou, Weinian, Warrington, Kenneth H., Srivastava, Arun
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598389/
https://ncbi.nlm.nih.gov/pubmed/16828834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.04.042
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