Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma‐prone families from three continents

BACKGROUND: The major factors individually reported to be associated with an increased frequency of CDKN2A mutations are increased number of patients with melanoma in a family, early age at melanoma diagnosis, and family members with multiple primary melanomas (MPM) or pancreatic cancer. METHODS: Th...

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Hlavní autoři: Goldstein, Alisa M, Chan, May, Harland, Mark, Hayward, Nicholas K, Demenais, Florence, Bishop, D Timothy, Azizi, Esther, Bergman, Wilma, Bianchi‐Scarra, Giovanna, Bruno, William, Calista, Donato, Albright, Lisa A Cannon, Chaudru, Valerie, Chompret, Agnes, Cuellar, Francisco, Elder, David E, Ghiorzo, Paola, Gillanders, Elizabeth M, Gruis, Nelleke A, Hansson, Johan, Hogg, David, Holland, Elizabeth A, Kanetsky, Peter A, Kefford, Richard F, Landi, Maria Teresa, Lang, Julie, Leachman, Sancy A, MacKie, Rona M, Magnusson, Veronica, Mann, Graham J, Bishop, Julia Newton, Palmer, Jane M, Puig, Susana, Puig‐Butille, Joan A, Stark, Mitchell, Tsao, Hensin, Tucker, Margaret A, Whitaker, Linda, Yakobson, Emanuel, Group, The Lund Melanoma Study
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2007
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598064/
https://ncbi.nlm.nih.gov/pubmed/16905682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.043802
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