Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a multistep testing approach in French‐Canadian families with high risk of breast and ovarian cancer

BACKGROUND AND OBJECTIVE: In clinical settings with fixed resources allocated to predictive genetic testing for high‐risk cancer predisposition genes, optimal strategies for mutation screening programmes are critically important. These depend on the mutation spectrum found in the population under co...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Simard, Jacques, Dumont, Martine, Moisan, Anne‐Marie, Gaborieau, Valérie, Vézina, Hélène, Durocher, Francine, Chiquette, Jocelyne, Plante, Marie, Avard, Denise, Bessette, Paul, Brousseau, Claire, Dorval, Michel, Godard, Béatrice, Houde, Louis, Joly, Yann, Lajoie, Marie‐Andrée, Leblanc, Gilles, Lépine, Jean, Lespérance, Bernard, Malouin, Hélène, Parboosingh, Jillian, Pichette, Roxane, Provencher, Louise, Rhéaume, Josée, Sinnett, Daniel, Samson, Carolle, Simard, Jean‐Claude, Tranchant, Martine, Voyer, Patricia, BRCAs, INHERIT, Easton, Douglas, Tavtigian, Sean V, Knoppers, Bartha‐Maria, Laframboise, Rachel, Bridge, Peter, Goldgar, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2007
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598057/
https://ncbi.nlm.nih.gov/pubmed/16905680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.044388
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge