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Somatic mutations of the epidermal growth factor receptor and non‐small‐cell lung cancer

Frequent overexpression of epidermal growth factor receptor (EGFR) in non‐small‐cell lung cancer (NSCLC) makes EGFR a new therapeutic target. Two specific EGFR tyrosine kinase inhibitors, gefitinib (ZD1839, Iressa) and erlotinib (OSI‐774, Tarceva), have been developed and approved by the US Food and...

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Détails bibliographiques
Auteurs principaux: Zhang, Xiaozhu, Chang, Alex
Format: Artigo
Langue:Inglês
Publié: BMJ Group 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598028/
https://ncbi.nlm.nih.gov/pubmed/17158592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.046102
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