Familial T‐cell non‐Hodgkin lymphoma caused by biallelic MSH2 mutations

Familial non‐Hodgkin lymphoma (NHL) is rare and in most cases, no underlying cause is identifiable. We report homozygous truncating mutations in the mismatch repair gene MSH2 (226C→T; Q76X) in three siblings who each developed T‐cell NHL in early childhood. All three children had hyperpigmented and...

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Bibliografiska uppgifter
Huvudupphovsmän: Scott, Richard H, Homfray, Tessa, Huxter, Nicola L, Mitton, Sally G, Nash, Ruth, Potter, Mike N, Lancaster, Donna, Rahman, Nazneen
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMJ Group 2007
Ämnen:
Online Mutation Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597999/
https://ncbi.nlm.nih.gov/pubmed/17601929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2007.048942
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