Mycobacterial lipoarabinomannan inhibits gamma interferon-mediated activation of macrophages.

The principal efferent role of the macrophage in acquired resistance to intracellular pathogens depends on activation by T-cell lymphokines, primarily gamma interferon (IFN-gamma). However, mouse macrophages that are heavily burdened with Mycobacterium leprae are refractory to activation by IFN-gamm...

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Udgivet i:Infect Immun
Main Authors: Sibley, L D, Hunter, S W, Brennan, P J, Krahenbuhl, J L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3128482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.5.1232-1236.1988
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