Differences in Lsh gene control over systemic Leishmania major and Leishmania donovani or Leishmania mexicana mexicana infections are caused by differential targeting to infiltrating and resident liver macrophage populations.

Earlier studies had shown that the viscerotropic NIH 173 strain of cutaneous Leishmania major fails to come under Lsh gene control. Visceral Leishmania donovani LV9 and another viscerotropic cutaneous strain, Leishmania mexicana mexicana LV4, are controlled by Lsh. The results of double-infection ex...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Davies, E V, Singleton, A M, Blackwell, J M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3356462/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.5.1128-1134.1988
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