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Paradigm shifts in the cell biology of STAT signaling
In recent years several of the key tenets of the original cytokine-STAT signaling paradigm have had to be revised. First, that nonphosphorylated “inactive” STATs are present in the cytoplasm as free monomers which dimerized only subsequent to Tyr-phosphorylation has been replaced by the understandin...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597702/ https://ncbi.nlm.nih.gov/pubmed/18691663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2008.07.003 |
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