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The mechanism of invariant NKT cell responses to viral danger signals

Invariant (i)NKT cells influence the response to viral infections, although the mechanisms are poorly defined. Here we show that these innate-like lymphocytes secrete IFN-γ upon culture with CpG oligodeoxynucleotide-stimulated dendritic cells (DCs) from mouse bone marrow. This requires TLR9 signalin...

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Hlavní autoři: Tyznik, Aaron J., Tupin, Emmanuel, Nagarajan, Niranjana A., Her, Min J., Benedict, Chris A., Kronenberg, Mitchell
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597678/
https://ncbi.nlm.nih.gov/pubmed/18802047
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