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Molecular Targeted Therapies in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with several genomic alterations. There is evidence of aberrant activation of several signaling cascades such as EGFR, Ras/ERK, PI3K/MTOR, HGF/MET, Wnt, Hedgehog and apoptotic signaling, Recently a multikinase inhibitor, sorafenib,...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597642/ https://ncbi.nlm.nih.gov/pubmed/18821591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22506 |
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