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Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin.

Bordetella pertussis and Bacillus anthracis produce extracytoplasmic adenylate cyclase toxins (AC toxins) with shared features including activation by calmodulin and the ability to enter target cells and catalyze intracellular cyclic AMP (cAMP) production from host ATP. The two AC toxins were evalua...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Gordon, V M, Leppla, S H, Hewlett, E L
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1988
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2895741/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.5.1066-1069.1988
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