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Early chimerism threshold predicts sustained engraftment and NK-cell tolerance in prenatal allogeneic chimeras

The failure of engraftment in human cases of in utero hematopoietic cell transplantation (IUHCT) in which no immunodeficiency exists suggests the presence of an unrecognized fetal immune barrier. A similar barrier in murine IUHCT appears to be dependent on the chimerism level and is poorly explained...

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Detalles Bibliográficos
Main Authors: Durkin, Emily T., Jones, Kelly A., Rajesh, Deepika, Shaaban, Aimen F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597617/
https://ncbi.nlm.nih.gov/pubmed/18796629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-128116
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