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Early chimerism threshold predicts sustained engraftment and NK-cell tolerance in prenatal allogeneic chimeras

The failure of engraftment in human cases of in utero hematopoietic cell transplantation (IUHCT) in which no immunodeficiency exists suggests the presence of an unrecognized fetal immune barrier. A similar barrier in murine IUHCT appears to be dependent on the chimerism level and is poorly explained...

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Detalhes bibliográficos
Main Authors: Durkin, Emily T., Jones, Kelly A., Rajesh, Deepika, Shaaban, Aimen F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597617/
https://ncbi.nlm.nih.gov/pubmed/18796629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-128116
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