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The APOE4 genotype alters the response of microglia and macrophages to 17β-estradiol

The apolipoprotein E4 (APOE4) gene is a well-known risk factor for Alzheimer’s disease (AD) and other neurological disorders. Post-menopausal women with AD who express at least one APOE4 gene have more severe neuropathology and worsened cognitive scores than their non-expressing counterparts. Since...

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Autors principals: Brown, Candice M., Choi, Emily, Xu, Qing, Vitek, Michael P., Colton, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597534/
https://ncbi.nlm.nih.gov/pubmed/17553597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.04.018
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