Chargement en cours...
Mutation of Tn5 transposase β-loop residues affects all steps of Tn5 transposition: the role of conformational changes in Tn5 transposition
X-ray co-crystal structures of Tn5 transposase (Tnp) bound to its 19 base pair (bp) recognition end sequence (ES) reveal contacts between a β-loop (amino acids 240-260) and positions 3, 4, 5 and 6 of the ES. Here we show that mutations of residues in this loop affect both in vivo and in vitro transp...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597523/ https://ncbi.nlm.nih.gov/pubmed/17176076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061227v |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|