Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens.

Four mycobacterial preparations directly stimulated human blood monocytes and alveolar macrophages to produce tumor necrosis factor (TNF). Monoclonal antibody against TNF blocked (99%) TNF activity. Lipopolysaccharide was not responsible for the TNF activity generated; activity was unaffected in the...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Valone, S E, Rich, E A, Wallis, R S, Ellner, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3053456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.12.3313-3315.1988
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