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Prediction of protein loop structures using a local move Monte Carlo approach and a grid-based force field

We have developed an improved local move Monte Carlo (LMMC) loop sampling approach for loop predictions. The method generates loop conformations based on simple moves of the torsion angles of side chains and local moves of backbone of loops. To reduce the computational costs for energy evaluations,...

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Detalhes bibliográficos
Main Authors: Cui, Meng, Mezei, Mihaly, Osman, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597363/
https://ncbi.nlm.nih.gov/pubmed/18957407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzn056
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