Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters

Molecular and pharmacological profiling of the NCI-60 cell panel offers the possibility of identifying pathways involved in drug resistance or sensitivity. Of these, decreased uptake of anticancer drugs mediated by efflux transporters represents one of the best studied mechanisms. Previous studies h...

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Main Authors: Okabe, Mitsunori, Szakács, Gergely, Reimers, Mark A., Suzuki, Toshihiro, Hall, Matthew D., Abe, Takaaki, Weinstein, John N., Gottesman, Michael M.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597359/
https://ncbi.nlm.nih.gov/pubmed/18790787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0539
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