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Cloning and expression in Escherichia coli of the perfringolysin O (theta-toxin) gene from Clostridium perfringens and characterization of the gene product.

The gene encoding perfringolysin O, the thiol-activated hemolysin from Clostridium perfringens (ATCC 13124), was cloned and expressed in Escherichia coli. A gene library of C. perfringens chromosomal DNA was constructed in bacteriophage lambda EMBL3. A recombinant was identified that produced a hemo...

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Detalhes bibliográficos
Publicado no:Infect Immun
Autor principal: Tweten, R K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259729/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2903127/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.12.3228-3234.1988
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