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Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product

BACKGROUND AND PURPOSE: The endocannabinoid virodhamine is a partial agonist at the cannabinoid CB(1) receptor and a full agonist at the CB(2) receptor, and relaxes rat mesenteric arteries through endothelial cannabinoid receptors. Its concentration in the periphery exceeds that of the endocannabino...

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Hlavní autoři: Kozłowska, H, Baranowska, M, Schlicker, E, Kozłowski, M, Laudañski, J, Malinowska, B
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597267/
https://ncbi.nlm.nih.gov/pubmed/18806815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.371
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