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Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cells

Since androgen receptor (AR) plays an important role in prostate cancer development and progression, androgen-ablation has been the frontline therapy for treatment of advanced prostate cancer even though it is rarely curative. A curative strategy should involve functional and structural elimination...

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Autors principals: Yang, Huanjie, Murthy, Shalini, Sarkar, Fazlul H., Sheng, Shijie, Reddy, G. Prem-Veer, Dou, Q. Ping
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597227/
https://ncbi.nlm.nih.gov/pubmed/18726991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21565
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