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Structural Basis for DNA Recognition by FoxO1 and its Regulation by Post-Translational Modification

FoxO transcription factors regulate the transcription of genes that control metabolism, cellular proliferation, stress tolerance and possibly lifespan. A number of post-translational modifications within the forkhead DNA binding domain regulate FoxO mediated transcription. We report the crystal stru...

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Main Authors: Brent, Michael M., Anand, Ruchi, Marmorstein, Ronen
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597217/
https://ncbi.nlm.nih.gov/pubmed/18786403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.06.013
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