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Differential p53 engagement in response to oxidative and oncogenic stresses in Fanconi anemia mice

Members of the Fanconi anemia (FA) protein family are involved in repair of genetic damage caused by DNA cross-linkers. It is not clear whether the FA proteins function in oxidative DNA damage and oncogenic stress response. Here we report that deficiency in the Fanca gene in mice elicits a p53-depen...

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Bibliografische gegevens
Hoofdauteurs: Rani, Reena, Li, Jie, Pang, Qishen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597211/
https://ncbi.nlm.nih.gov/pubmed/19047147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1790
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