Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function

Down-regulation of the forkhead transcription factor Foxp1 by integrin engagement controls monocyte differentiation in vitro. To determine whether Foxp1 plays a critical role in monocyte differentiation and macrophage functions in vivo, we generated transgenic mice (macFoxp1tg) overexpressing human...

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Autores principales: Shi, Can, Sakuma, Masashi, Mooroka, Toshifumi, Liscoe, Alison, Gao, Huiyun, Croce, Kevin J., Sharma, Arjun, Kaplan, David, Greaves, David R., Wang, Yunmei, Simon, Daniel I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2008
Materias:
Phagocytes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597137/
https://ncbi.nlm.nih.gov/pubmed/18799727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-137018
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