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Adenoviral ER-targeted mda-7/IL-24 vector enhances human cancer cell killing

We developed several adenoviral vectors designed to target MDA-7 expression to different subcellular compartments (ie, ER, mitochondria, nucleus, and cytosol) and evaluated their ability to enhance apoptosis. Adenoviral ER-targeted mda-7/IL-24 vector (Ad-ER-mda7) selectively and effectively inhibite...

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Detalhes bibliográficos
Main Authors: Pataer, Abujiang, Hu, Wenxian, Xiaolin, Lu, Chada, Sunil, Roth, Jack A., Hunt, Kelly K., Swisher, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597048/
https://ncbi.nlm.nih.gov/pubmed/18723497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0083
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