Downregulation of Transcription Factor Peroxisome Proliferator-activated Receptor in Programmed Hepatic Lipid Dysregulation and Inflammation in Intrauterine Growth Restricted Offspring

OBJECTIVE: Intrauterine growth restricted newborns (IUGR) have increased risk of obesity-induced “fatty liver” and inflammation. We hypothesized that IUGR-induced inhibition of hepatic peroxisome proliferator activated receptors (PPARs) is associated with an increased inflammatory response. STUDY DE...

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Главные авторы: MAGEE, Thomas R., HAN, Guang, Cherian, Bindu, KHORRAM, Omid, ROSS, Michael G., DESAI, Mina
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597035/
https://ncbi.nlm.nih.gov/pubmed/18667178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2008.05.022
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