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Prenatal Androgen Excess Negatively Impacts Body Fat Distribution in a Nonhuman Primate Model of Polycystic Ovary Syndrome (PCOS)

INTRODUCTION: Prenatally androgenized (PA) female rhesus monkeys share metabolic abnormalities in common with PCOS women. Early gestation exposure (E) results in insulin resistance, impaired pancreatic beta-cell function and type 2 diabetes, while late gestation exposure (L) results in supranormal i...

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Main Authors: Bruns, Cristin M, Baum, Scott T, Colman, Ricki J, Dumesic, Daniel A, Eisner, Joel R, Jensen, Michael D, Whigham, Leah D, Abbott, David H
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597033/
https://ncbi.nlm.nih.gov/pubmed/17471299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.ijo.0803638
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