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Carbonylation of Epoxides to Substituted 3-Hydroxy-δ-Lactones

[Image: see text] Substituted 3-hydroxy-δ-lactones (3HLs) are valuable intermediates in the synthesis of pharmaceuticals and other biologically active natural products. Herein we report the first example of the catalytic carbonylation of substituted homoglycidols to 3HLs using HCo(CO)(4). Upon optim...

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Autores principales: Kramer, John W., Joh, Daniel Y., Coates, Geoffrey W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596996/
https://ncbi.nlm.nih.gov/pubmed/18027958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol702475e
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