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Carbonylation of Epoxides to Substituted 3-Hydroxy-δ-Lactones

[Image: see text] Substituted 3-hydroxy-δ-lactones (3HLs) are valuable intermediates in the synthesis of pharmaceuticals and other biologically active natural products. Herein we report the first example of the catalytic carbonylation of substituted homoglycidols to 3HLs using HCo(CO)(4). Upon optim...

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Detalles Bibliográficos
Main Authors: Kramer, John W., Joh, Daniel Y., Coates, Geoffrey W.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596996/
https://ncbi.nlm.nih.gov/pubmed/18027958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol702475e
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