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Agrin Signalling Contributes to Cell Activation and Is Overexpressed in T Lymphocytes from Lupus Patients

It is shown in this study that the heparan sulfate proteoglycan agrin is overexpressed in T cells isolated from patients with the autoimmune disease systemic lupus erythematosus (SLE). Freshly isolated CD4(+) and CD8(+) subpopulations both exhibited higher expression over healthy controls, which how...

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Detalles Bibliográficos
Autores principales: Jury, Elizabeth C., Eldridge, Jillian, Isenberg, David A., Kabouridis, Panagiotis S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596879/
https://ncbi.nlm.nih.gov/pubmed/18025246
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