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Quantitative Tissue and Gene Specific Differences and Developmental Changes in Nat1, Nat2 and Nat3 mRNA Expression in the Rat
Human N-acetyltransferase 1 (NAT1) and 2 (NAT2) are important phase II enzymes involved in the biotransformation of xenobiotics. In toxicity and carcinogenicity studies, functional polymorphism of rat N-acetyltransferase is considered a model for similar human variability. To accurately quantitate e...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596640/ https://ncbi.nlm.nih.gov/pubmed/18799802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.023564 |
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