DIFFERENTIAL REGULATION OF PC1/3, PC2 AND PHOSPHORYLATED CREB BY SHORT-TERM AND LONG-TERM MORPHINE TREATMENT: IMPLICATIONS FOR UNDERSTANDING THE “SWITCH” TO OPIATE ADDICTION

Drug addiction is a state of altered brain reward and self-regulation mediated by both neurotransmitter and hormonal systems. Although an organism’s internal system attempts to maintain homeostasis when challenged by exogenous opiates and other drugs of abuse, it eventually fails, resulting in the t...

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Autores principales: ESPINOSA, VERONICA PAEZ, LIU, YANJUN, FERRINI, MONICA, ANGHEL, ADRIAN, NIE, YING, TRIPATHI, PINKY V., PORCHE, RENE, JANSEN, ERIK, STUART, RONALD C., NILLNI, EDUARDO A., LUTFY, KABIRULLAH, FRIEDMAN, THEODORE C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596639/
https://ncbi.nlm.nih.gov/pubmed/18771713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.07.063
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