Nicotine Acts on Growth Plate Chondrocytes to Delay Skeletal Growth through the α7 Neuronal Nicotinic Acetylcholine Receptor

BACKGROUND: Cigarette smoking adversely affects endochondral ossification during the course of skeletal growth. Among a plethora of cigarette chemicals, nicotine is one of the primary candidate compounds responsible for the cause of smoking-induced delayed skeletal growth. However, the possible mech...

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Detalhes bibliográficos
Main Authors: Kawakita, Atsuo, Sato, Kazuki, Makino, Hatsune, Ikegami, Hiroyasu, Takayama, Shinichiro, Toyama, Yoshiaki, Umezawa, Akihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596484/
https://ncbi.nlm.nih.gov/pubmed/19079602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003945
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