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Cholinergic Neuromodulation Changes Phase Response Curve Shape and Type in Cortical Pyramidal Neurons

Spike generation in cortical neurons depends on the interplay between diverse intrinsic conductances. The phase response curve (PRC) is a measure of the spike time shift caused by perturbations of the membrane potential as a function of the phase of the spike cycle of a neuron. Near the rheobase, pu...

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Autors principals: Stiefel, Klaus M., Gutkin, Boris S., Sejnowski, Terrence J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596483/
https://ncbi.nlm.nih.gov/pubmed/19079601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003947
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