Abnormal Patterns of Lipoprotein Lipase Release into the Plasma in GPIHBP1-deficient Mice

GPIHBP1-deficient mice (Gpihbp1(–/–)) exhibit severe chylomicronemia. GPIHBP1 is located within capillaries of muscle and adipose tissue, and expression of GPIHBP1 in Chinese hamster ovary cells confers upon those cells the ability to bind lipoprotein lipase (LPL). However, there has been absolutely...

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Bibliographic Details
Main Authors: Weinstein, Michael M., Yin, Liya, Beigneux, Anne P., Davies, Brandon S. J., Gin, Peter, Estrada, Kristine, Melford, Kristan, Bishop, Joseph R., Esko, Jeffrey D., Dallinga-Thie, Geesje M., Fong, Loren G., Bensadoun, André, Young, Stephen G.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596386/
https://ncbi.nlm.nih.gov/pubmed/18845532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806067200
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