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Diabetes downregulates BKβ1 potassium channel subunit in retinal arteriolar smooth muscle

Retinal vasoconstriction and reduced retinal blood flow precede the onset of diabetic retinopathy. The pathophysiological mechanisms that underlie increased retinal arteriolar tone during diabetes remain unclear. Normally, local Ca(2+) release events (Ca(2+)-sparks), trigger the activation of large-...

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Detalhes bibliográficos
Main Authors: McGahon, MK, Dash, DP, Arora, A, Wall, N, Dawicki, J, Simpson, DA, Scholfield, CN, McGeown, JG, Curtis, TM
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596350/
https://ncbi.nlm.nih.gov/pubmed/17293477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000260182.36481.c9
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