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Structural Biology of the Purine Biosynthetic Pathway

Purine biosynthesis requires ten enzymatic transformations to generate inosine monophosphate. PurF, PurD, PurL, PurM, PurC, and PurB are common to all pathways, while PurN or PurT, PurK/PurE-I or PurE-II, PurH or PurP, and PurJ or PurO catalyze the same steps in different organisms. X-ray crystal st...

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Main Authors: Zhang, Yang, Morar, Mariya, Ealick, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596281/
https://ncbi.nlm.nih.gov/pubmed/18712276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-8295-8
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