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Influence of intranasal immunization with synthetic peptides corresponding to conserved epitopes of M protein on mucosal colonization by group A streptococci.

A major virulence factor of group A streptococci is M protein, a surface-exposed fibrillar molecule of which there exist more than 80 distinct serological types. Antigenic variability resides largely in the amino-terminal region of M protein, whereas the carboxy-terminal half of the molecule is high...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Bessen, D, Fischetti, V A
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1988
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259627/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2458320/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.10.2666-2672.1988
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