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Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice

The recent development of small-molecule tyrosine kinase (TK) inhibitors offers increasing opportunities for the treatment of autoimmune diseases. In this study, we investigated the potential of this new class of drugs to treat and cure type 1 diabetes (T1D) in the NOD mouse. Treatment of prediabeti...

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Autores principales: Louvet, Cédric, Szot, Gregory L., Lang, Jiena, Lee, Michael R., Martinier, Nicolas, Bollag, Gideon, Zhu, Shirley, Weiss, Arthur, Bluestone, Jeffrey A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596241/
https://ncbi.nlm.nih.gov/pubmed/19015530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810246105
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