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E2F4 Function in G(2): Maintaining G(2)-Arrest to Prevent Mitotic Entry with Damaged DNA

Mammalian cells undergo cell cycle arrest in response to DNA damage through multiple checkpoint mechanisms. One such checkpoint pathway maintains genomic integrity by delaying mitotic progression in response to genotoxic stress. Transition though the G(2) phase and entry into mitosis is considered t...

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Detalhes bibliográficos
Main Authors: Plesca, Dragos, Crosby, Meredith E., Gupta, Damodar, Almasan, Alexandru
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596058/
https://ncbi.nlm.nih.gov/pubmed/17507799
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