Direct cytotoxic action of Shiga toxin on human vascular endothelial cells.

To help explain a role of the Shiga toxin family in hemorrhagic colitis and hemolytic-uremic syndrome in humans, it has been hypothesized that these toxins cause direct damage to the vascular endothelium. We now report that Shiga toxin purified from Shigella dysenteriae 1 does indeed have a direct c...

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Hauptverfasser: Obrig, T G, Del Vecchio, P J, Brown, J E, Moran, T P, Rowland, B M, Judge, T K, Rothman, S W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC259575/
https://ncbi.nlm.nih.gov/pubmed/3044997
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