Advanced gastrointestinal stromal tumors successfully treated with imatinib mesylate: a report of two cases.

Activation of kit-receptor tyrosine kinase occurs in all cases of gastrointestinal stromal tumors, regardless of the mutation status of kit. Imatinib mesylate (STI 571,Gleevec) is a selective inhibitor of certain protein tyrosine kinases. It has been shown in preclinical models and clinical studies...

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Bibliografiske detaljer
Main Authors: Hasan, Syed, Hassan, Mohamed, Oke, Luc, Dinh, Kimberly, Onojobi, Gladys, Lombardo, Fred, Dawkins, Fitzroy, Jack, Momodu
Format: Artigo
Sprog:Inglês
Udgivet: National Medical Association 2003
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2594846/
https://ncbi.nlm.nih.gov/pubmed/14717479
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