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The glucagon receptor is required for the adaptive metabolic response to fasting
Glucagon receptor (Gcgr) signaling maintains hepatic glucose production during the fasting state however the importance of the Gcgr for lipid metabolism is unclear. We show here that fasted Gcgr-/- mice exhibit a significant increase in hepatic triglyceride secretion and fasting increases fatty acid...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593715/ https://ncbi.nlm.nih.gov/pubmed/19046568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.09.008 |
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