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Multigenome DNA sequence conservation identifies Hox cis-regulatory elements

To learn how well ungapped sequence comparisons of multiple species can predict cis-regulatory elements in Caenorhabditis elegans, we made such predictions across the large, complex ceh-13/lin-39 locus and tested them transgenically. We also examined how prediction quality varied with different geno...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuntz, Steven G., Schwarz, Erich M., DeModena, John A., De Buysscher, Tristan, Trout, Diane, Shizuya, Hiroaki, Sternberg, Paul W., Wold, Barbara J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593573/
https://ncbi.nlm.nih.gov/pubmed/18981268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.085472.108
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