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Roles of cell and microvillus deformation and receptor-ligand binding kinetics in cell rolling

Polymorphonuclear leukocyte (PMN) recruitment to sites of inflammation is initiated by selectin-mediated PMN tethering and rolling on activated endothelium under flow. Cell rolling is modulated by bulk cell deformation (mesoscale), microvillus deformability (microscale), and receptor-ligand binding...

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Detalhes bibliográficos
Main Authors: Pawar, Parag, Jadhav, Sameer, Eggleton, Charles D., Konstantopoulos, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593528/
https://ncbi.nlm.nih.gov/pubmed/18660437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.91536.2007
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