Formation and function of ceramide-enriched membrane platforms with CD38 during M(1)-receptor stimulation in bovine coronary arterial myocytes

CD38 contains an ADP ribosylcyclase domain that mediates intracellular Ca(2+) signaling by the production of cyclic ADP-ribose (cADPR), but the mechanisms by which the agonists activate this enzyme remain unclear. The present study tested a hypothesis that a special lipid-raft (LR) form, ceramide-en...

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Hauptverfasser: Jia, Su-Jie, Jin, Si, Zhang, Fan, Yi, Fan, Dewey, William L., Li, Pin-Lan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2008
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593517/
https://ncbi.nlm.nih.gov/pubmed/18723763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00617.2008
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