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Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension

This study determined if altered vascular prostacyclin (PGI(2)) and/or thromboxane A(2) (TxA(2)) production with reduced Po(2) contributes to impaired hypoxic dilation of skeletal muscle resistance arterioles of obese Zucker rats (OZRs) versus lean Zucker rats (LZRs). Mechanical responses were asses...

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Hlavní autoři: Goodwill, Adam G., James, Milinda E., Frisbee, Jefferson C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593516/
https://ncbi.nlm.nih.gov/pubmed/18689495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00596.2008
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