Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves

Extracellular matrix remodeling has been proposed as one mechanism by which proximal pulmonary arteries stiffen during pulmonary arterial hypertension (PAH). Although some attention has been paid to the role of collagen and metallomatrix proteins in affecting vascular stiffness, much less work has b...

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Detalhes bibliográficos
Main Authors: Lammers, Steven R., Kao, Phil H., Qi, H. Jerry, Hunter, Kendall, Lanning, Craig, Albietz, Joseph, Hofmeister, Stephen, Mecham, Robert, Stenmark, Kurt R., Shandas, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593497/
https://ncbi.nlm.nih.gov/pubmed/18660454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00127.2008
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